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The Scientific Notes of the Pavlov University

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Vol 26, No 2 (2019)
View or download the full issue PDF (Russian)
https://doi.org/10.24884/1607-4181-2019-26-2

HEALTH CARE ORGANIZATION

12-17 1062
Abstract

The objective was to assess the health status of school-age children living in rural areas.

Material and methods. The study was carried out by the method of the main array by anonymous questioning of 106 schoolchildren of grades 7–11 at the age of 12–17 years, trained in the municipal general education institution «Secondary School № 1» in the city Dno of the Pskov Region. The information obtained from Form № 026/y-2000 was used for an objective assessment.

Results. We determined that 52.8 % of the children who studied at the rural school in grades 7–11 were girls whose average age was (14.72±0.2) years, brought up in a full family (69.8 %) with two children (48.2 %), with a good financial situation (52.9 %). Studying self-esteem of schoolchildren’s health showed that the average score set by children was (3.86±0.08). Girls are worse than boys, they evaluate their health. The study of the frequency of acute diseases in children and the number of days missed by them due to disease during the school year showed that the average number of diseases was (1.61±0.19) times, the number of missed days was (7.9±0.76) days. We found out that only 18.8 % of children did not go to school when they were sick. 63.2 % of children were engaged in sports, while 30.2 % were engaged in sports regularly. All 100.0 % of boys were more or less engaged in sports, among them 64.0 % of schoolchildren were regularly engaged in sports. Among girls, no one was regularly engaged in sports, 30.4 % was irregularly engaged in sports. Studying the attitude of schoolchildren to smoking and drinking alcoholic drinks showed that 8.5 % of schoolchildren smoked regularly, 15.1 % of schoolchildren drank low-alcohol drinks from time to time, 18.9 % – wine, and 4.7 % of schoolchildren – strong spirits. According to medical records, more than half of schoolchildren had disharmonious physical development (55.8 %). The estimation of the distribution of children by health groups showd that among schoolchildren the proportion of children of group I was 21.4 %, group II – 59.1 %, group III – 17.7 %, group IV – 1.8 %, groups V – 0 %.

Conclusion. Indicators of self-assessment of schoolchildren’s health and the proportion of children involved in sports in the Pskov Region were lower than on the average in the Russian Federation. The health level of schoolchildren living in rural areas was lower than the average Russian indicators.

REVIEWS AND LECTURES

9-11 988
Abstract

Surgical treatment of obesity and associated diseases, like any other field of practical medicine, is based on certain laws and conditions. All the principles of bariatric surgery were formulated in the process of accumulating a positive and negative experience of using various surgical interventions. The article presents an historical perspective on the evolution of views on the fundamental principles of the operative treatment of obesity and associated diseases.

ORIGINAL PAPERS

18-27 935
Abstract

Relevance. Cervical cancer – one of malignant new growths most often met among women. Intraepithelial changes precede to it; these changes can disappear spontaneously or progress to cancer. For the present moment, there are no markers describing the outcome of cervical intraepithelial neoplasia.

The objective was to research the expression L1 HPV and NuMA1 as factors of prognosis HPV-positive cervical intraepithelial neoplasias by high-risk human papillomavirus.

Material and methods. The biopsies of 178 women from HPV-positive cervical neoplasias were studied by cytological, histological, immunocytochemical methods and PCR.

Results. We verified HPV-HR-positive: mild (42.7 %), moderate (34.27 %), severe (21.91 %) dysplasias, Ca in situ (1.12 %). In 81.13 % of researches, CIN with expression of L1 and NuMA1 had regression of dysplasia, in 13.21 % – persistence of grade squamous intraepithelial lesion, in 5.66 % – progression of dysplasia. In 73.33 % of cases, CIN with expression of NuMA1 had regression, in 26.67 % – persistence of dysplasia. In 45.45 % of researches, CIN with expression of L1 had regression of dysplasia, in 48.48 % – persistence of grade squamous intraepithelial lesion, in 6.06 % – progression of dysplasia. Regression or progression of dysplasia with expression L1 and NuMA1 or one of these proteins for the first time was revealed later 6 months.

Conclusion. CIN could come to the end with regression, persistence or progression. At expression of atypical cells L1 and NuMA1, the greatest quantity – 81.13 %, of cases of CIN regression was noted. At expression of atypical cells only NuMA1, CIN came to the end with regression or long persistence. Course of CIN with expression L1 HPV was characterized by the greatest parameters of persistence and progression marked, accordingly, in 48.48 and 6.06 % of cases.

28-36 968
Abstract

The objective was the objective assessment of the main osteo-specific laboratory and instrumental diagnostic indicators and their prognostic effect on the outcome of surgical treatment.

Material and methods. The study included 72 patients who were divided into 2 groups: 35 (48.6 %) patients with a satisfactory outcome after surgery for year, and 37 (51.4 %) patients with various postoperative complications.

Results. The highest statistical significance was indicated by the level of serum vitamin D (p<0.001) and the level of fibrinogen (p<0.001). The average value of the Hounsfield index in the group of patients without complications was 164.5 (Me 51.2), in the group of patients with complications – 71.5 (Me 85.0). The statistical significance (p<0.001) of the Hounsfield index between the two groups of patients was noted. The highest statistical significance was indicated by the level of serum vitamin D (p<0.001) and the level of fibrinogen (p<0.001). A discriminant analysis was performed with the construction of canonical correlation based on the results of laboratory and instrumental indices in order to determine the relationship between the obtained parameters and infectious and common complications.

Conclusion. The discriminant prediction formula for infectious complications among patients planned for hip / knee arthroplasty obtained during the study had a high sensitivity (90 %) and specificity (87.1 %).

37-40 805
Abstract

Introduction. Surgical treatment of obese patients includes a high risk of complications.

Material and methods. The article presents the analysis of the informativeness and reliability of OS-MRS, E. Livingston, P. Turner scores in predicting postoperative complications in patients with overweight and metabolic disorders.

Results. According to the study, the OS-MRS score was the most reliable.

41-46 899
Abstract

Introduction. The need for software for targeted epidemiological monitoring of patients with high risk of infection in surgical procedures is obvious at present.

The objective of the study was the scientific substantiation of the content of the epidemiological module of the electronic medical records of patients with surgical diseases.

Material and methods. Retrospective analysis of data on infectious complications in the area of surgical intervention in patients of 42 hospitals of St. Petersburg over the past 10 years.

Results. The incidence rate of surgical sites infections in hospitals of St. Petersburg for many years did not exceed 0.3 per 100 operations, due to the lack of reliable monitoring data of observations of postoperative infectious complications in the city institutions. We defined the list of parameters to be recorded in the electronic medical record during surgical treatment of pathology for the organization of systematic monitoring of the course of pathophysiological changes in the area of operation, taking into account the overall clinical assessment of the quality of medical care.

Conclusion. The use of the epidemiological module in the electronic medical record would allow timely and purposefully to carry out preventive measures on creating conditions for the uncomplicated course of the postoperative period in patients who underwent surgery in the hospital.

47-55 7772
Abstract

The objective of the study was the analysis and evaluation of patients` intellectual and memory impairments before and after resection of brain glioma

Material and methods. We performed the study of 30 patients with brain glioma. The diagnosis of the studied patients was based on clinical and laboratory data, data of radiation and instrumental methods of research. The analysis of patients` intellectual and memory impairments was carried out in the preoperative and early, late postoperative periods. The patients` age ranged from 25 to 65 years; the median age was 56.5 year. In the present study, we used the following tests: intelligence tests – Amthauer test (for persons under 60 years), Raven test; memory tests – 10 word memorization test, Wechsler memory scale.

Results. We revealed regression of various memory (from 100 to 96.7 %) and intellectual disorders (from 20 to 3.3 %; p<0.05). Short-term memory in patients with brain glioma revealed more pronounced changes in comparison with long-term memory disorders after surgery. Improvement of verbal and logical memory, visual and associative memory after surgical treatment was found. In the late postoperative period, there was an increase in the intelligence coefficient (p<0.05), a decrease in the number of patients with severe dementia (from 16.7 to 3.3 %) and an average intelligence level (from 30 to 13.3 %) (p<0,05). 

Conclusion. The study revealed that surgery led to regression of intellectual and memory disorders in patients with brain glioma.

56-61 1358
Abstract

Relevance. The relevance of improving the treatment of pregnant women with iron deficiency anemia (IDA) is due to an increase in morbidity and adverse effects on the course and outcome of the gestational process, the state of the fetus and newborn.

The objective of this study was the comparative assessment of the frequency of complications of labor and the postpartum period in women who received intravenous and oral iron preparations during pregnancy.

Material and methods. The study included 140 pregnant women. The mean age of the patients was 31.75 (19; 49) years. 

Results. Pregnant women with IDA, after a single administration of intravenous preparation of iron carboxymaltosate, had pronounced stable dynamics of hematological and ferrokinetic blood parameters, as well as the low frequency of postpartum complications, compared to the oral preparation of iron (III) hydroxide polymaltosate.

62-68 1149
Abstract

Introduction. This article is devoted to psychological features in patients with pain syndrome in endometriosis and their pain perception.

The objective of the study was to identify features of pain syndrome perception, personality traits, emotional features and satisfaction with quality of life in patients with endometriosis.

Material and methods. 56 women were examined: 27 patients with endometriosis and 29 women without gynecological diseases. The following psychodiagnostic methods were used: «The McGill Pain Questionnaire», «Visual Analogue Scale», «Giessen test», the test of L. N. Sobchik «Diagnosis of interpersonal relationships», the questionnaire of N. E. Vodopyanova «Assessment of the level of satisfaction with the quality of life», «Hospital Anxiety and Depression Scale» (HADS).

Results. The results of the study indicated that patients with painful forms of endometriosis were less satisfied with the quality of life in the field of health, emotional and physical comfort. The feminine type of gender-role behavior was identified in self-perception, and the responsibly-magnanimous style prevails in interpersonal relations. The perception of pain was interrelated with interpersonal behavior style.

Conclusion. Psychological characteristics of patients with endometriosis must have been taken into account during treatment and rehabilitation, since they affected the subjective perception of pain, could reduce satisfaction with the quality of life and worsen the emotional state.

69-81 1143
Abstract

Introduction. There are key problems that limit patients’ functioning in the period after insult. The content of these problems determines the structure of multidisciplinary team.

The objective of the study was to describe key problems that limited patients’ functioning in the period after insult and determine the structure of multidisciplinary team for resolving these problems efficiently.

Material and methods. The study was observational. The sample size was 81 patients. Inclusion criteria: acute phase of post ischemic or hemorrhagic stroke (0–14 days after onset), mRs score 2 and more at admission to the hospital, the age over 18 years. Exclusion criteria: patients with transient ischemic attack, subarachnoid haemorrhage, Glasgow coma scale 2 and more at admission to the hospital. All patients – research participants received medical care in according to clinical guidelines, and multidisciplinary rehabilitation. In the course of rehabilitation, the first and second key problems that limited patients’ functioning in the period after insult were dedicated in each patient. We also investigated these problems and explored, which specialists must have been included in the structure of multidisciplinary team.

Results. The key problems were non-medical in 24 % cases, poor exercise capacity were presented in 27 % cases, environment issues – 6 % cases, swallowing and speech disorders – 17 %, nursery problems – 4 %. The next specialists were needed to resolve the key problems: psychologist – 38 % cases, physical therapist– 69 % cases, occupational therapist – 28 % cases, neurologist – 27 % cases, physical medicine and rehabilitation physician – 27 % cases.

Conclusion. Medical (rehabilitation physician, specialist, nurse) and non-medical specialists (occupational therapist, physical therapist, psychologist, logopaedist, etc.) must have been included in multidisciplinary team.



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ISSN 1607-4181 (Print)
ISSN 2541-8807 (Online)