Social contacts of 623 lonely and living alone 60-and- older seniors were studied. A considerable part of respondents indicated the existence of social contacts with relatives (71.9 %) and neighbors, friends, acquaintances (94.2 %). The majority of respondents preferred health and social care though only 69.5 % of respondents could rely on relatives (67.7 % of lonely seniors and 71.4 % living alone seniors).

2175 of patients were interviewed in 2014 year. The index of female patients' satisfaction of medical care in antenatal clinic is 0.88 but there are differences on some aspects of medical care and in districts of Saint Petersburg. It was recommended to use the obtained data for improving the availability of medical care.

Nowadays, only few cases of simultaneous cerebral arterial and venous thrombosis were reported. However, there might be high probability of coexisted cerebral arterial and venous changes. It is worthy to study the reasons and frequency of these coexisted vascular changes contributing to the development of clinical pictures. We analyzed 12 cases of simultaneous cerebral and/or neck vascular changes based on vascular images and ultrasonography which were divided into 4 groups: coexistence of simultaneous arterial and venous thrombosis; venous thrombosis with arterial hypoplasia; arterial thrombosis, arteritis or dissections with venous sinus hypoplasia; coexistence of arterial and venous hypoplasia.

In spite of age and blood pressure values at rest,hypertensive response to moderate intensity stress testingis characterized by increasing ofprobable beginning of cardiac infarction, stroke or coronary disease in 1.36 times. The hypertensive response to stress test in people with normal blood pressure values at rest (independent of other risk factors) is characterized by increasing risk of future hypertension more than in 2 times. Antihypertensive drugs affect blood pressure values differently during the stress testing. The prognosis of blood pressure values during daily physical activity is necessary for antihypertensive treatment. Low availability of convenient instruments and methodological tools for continuous measurement of blood pressure (similar to Spiroarteriocardiorhythmograph, Finapres) duringthe dosed physical loads constrain wide use of stress tests with controlled blood pressure in medical practice.

The research represents working out of non-invasive colorectal cancer screening based on DNA integrity testing of patient's fecal. Polymerase chain reaction method and the following polyacrylamide gel electrophoresis in fecal of patient with colorectal cancer detected long DNA fragments which size was 800 n.p. But the same stool DNA testing of control group detected just short DNA fragments which size was less than 200 n.p. The sensitivity and specificity of the analysis was 71 (р<0,0001) и 100 % (р<0,0001).

The conducted studies indicate that before the beginning of antituberculous treatment TB patients with homeostatic equilibrium disorder depending on the phase state of the specific process in the lungs, the expression of the intoxication syndrome, the extent of lung tissue damage and the age of the patients. Increasing of BHE(body homeostatic equilibrium) disfunction rate is followed by upraise of defective adaptive reactions. LLI indicators intend for BHE evaluation, H and R of the formed elements of the white bloodcellsintend to state the degree of BHE disfunction.

The article represents the results of research of correlation between the coping behavior and types of attitude to the disease taking into account the emotional, behavioral and cognitive components in male patients with different types of acute coronary heart disease (acute myocardial infarction and unstable stenocardia). Recommendations for the elaborating of psychocorrectional program were given according to the analysis of the obtained data.

The efficiency rating of the treatment in patients with Meniere's disease was performed with the help of different methods in accordance to vestibular function for the early term (in 3 months) after treatment. Improvement of clinical course was observed in all groups of patients. However. complex therapy became the most effective method which included pneumomassage of labyrinthine windows and kinesitherapy. The article shows advantages of complex therapy over the medication therapy according to assessment of vestibular dysfunction.

It was revealed that melancholic and phlegmatic had the lowest content of high-density lipoprotein and the highest content atherogenic lipid fractions combined with maximum activity and weight of lipoprotein-associated phospholipase A2 as well as the highest quantity of people with complications of hypertension among the examined patients. The ratio of people with complications in groups of choleric and sanguine with high level of anxiety and phlegmatic and melancholic with high level of anxiety was 1: 2.

The differential diagnosis of alcoholic and dilated cardiomyopathy according to the macroscopic data is represented in the article. The identity of macroscopic changes of heart, related to alcoholic and dilated cardiomyopathy, cannot diagnose these diseases based on the macroscopic characteristics; especially if there are no other visceral manifestations typical for chronic alcoholism.

The incidence of esophageal adenocarcinoma among the population in economically developed countries has been increasing significantly for last three decades. Columnar-lining esophagus (Barrett's esophagus) is one of the proven factors of developing esophagus cancer. The prevalence of Barrett's esophagus and esophageal adenocarcinoma in Russia is not investigated enough. The analysis of the results of 34903 endoscopic examinations of the upper gastrointestinal tract in population of Leningrad region with symptoms of gastric dyspepsia during the period from 2007 to 2013 is presented in this article.

This review introduces readers to the problems of improvement in dental care among the residents of industrial district in megalopolis and the main methods of prevention of dental diseases. The presented data demonstrate the features of dental status of population in industrial district in megalopolis. The article describes the basic ways of prevention of dental diseases and the rules of oral hygiene among the population.

Clinical presentations of disorders of the nervous system manifest in young and middle-aged patients with congenital and acquired mitochondrial dysfunctions and cognitive disorders manifest in patients with mitochondrial diseases more often. Nowadays the effective methods of initial diagnosing of these conditions are neurological and neuropsychological examination of patients, using of biochemical markers of mitochondrial diseases: the indices of lactate, total homocysteine in plasma and liquor. Neuro-visual study (Magnetic resonance imaging of the brain, MR spectroscopy, tractography, diffusion-weighted magnetic resonance imaging of the brain, mitochondrial DNA typing) is actually used for the differential diagnosing of mitochondrial diseases with other disorders that are accompanied by demyelinating disorders.

There were no statistically significant differences in the initial period of serving the sentence by all parameters of time perspective regardless of gender and the number of the previous records of acquisitive crime. A phenomenon of «perceptual distortion of course of life in the time continuum» was revealed. The degree of its manifestation affects the success of adaptation in the initial period of serving the sentence.

This article is devoted to the 75 year anniversary of MD, professor, Eugene Schwartz. It represents the steps of his life and work, his scientific achievements. It shows the role of E. I. Schwartz in the development of molecular-genetic methods and their introduction into medical practice as well as his contribution to such field as molecular medicine.

Humanities and social sciences were practically excluded from the educational programs of medical departments in institutes till the early 20^th century. The article describes how these disciplines became the integral part for medical education by the 1930^th. Major topics of the article are the causes which led to the inclusion of these disciplines in educational programs and influence of thе Revolution of 1917 on this process.