A rare case of toxoplasmosis encephalomyelitis in a patient with HIV infection
https://doi.org/10.24884/1607-4181-2026-33-1-133-141
Abstract
CNS toxoplasmosis is a relatively frequent complication of HIV infection, most commonly involving brain lesions. However, there are only a few publications reporting cases of toxoplasmosis associated myelitis or encephalomyelitis. In this article, we present a rare clinical case of encephalomyelitis in a 53-year-old patient with newly diagnosed HIV infection in the stage of severe immunodeficiency. The patient additionally developed haematological side effects from specific anti toxoplasmosis therapy, which were successfully managed. Despite of the late initiation of etiotropic therapy, clinical, laboratory, and neuroimaging improvement was observed by the 51st day of specific treatment.
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About the Authors
A. V. Koloteva
Center for Prevention and Control of AIDS and Infectious Diseases; Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Koloteva Anna V., Neurologist, Center for Prevention and Control of AIDS and Infectious Diseases; Post-graduate Student of the Department of Neurology, Pavlov University
179, Obvodny Canal Embankment, Saint Petersburg, 198103
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Author declares no conflict of interest.
E. M. Bazyuk
Center for Prevention and Control of AIDS and Infectious Diseases; Smorodintsev Research Institute of Influenza
Russian Federation
Competing Interests:
Russian Federation
Evgenia M., Head of the 3rd Infectious Diseases Department, Center for Prevention and Control of AIDS and Infectious Diseases; Postgraduate Student, Smorodintsev Research Institute of Influenza
179, Obvodny Canal Embankment, Saint Petersburg, 198103
15/17, Prof. Popova str., Saint Petersburg, 197022
Competing Interests:
Author declares no conflict of interest.
N. V. Shuleshova
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Shuleshova Natalya V., Dr. of Sci. (Med.), Professor, Professor of the Department of Neurology
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Author declares no conflict of interest.
T. N. Vinogradova
Center for Prevention and Control of AIDS and Infectious Diseases
Russian Federation
Competing Interests:
Russian Federation
Vinogradova Tatiana N., Cand. of Sci. (Med.), Chief Physician, Center for Prevention and Control of AIDS and Infectious Diseases
179, Obvodny Canal Embankment, Saint Petersburg, 198103
Competing Interests:
Author declares no conflict of interest.
E. V. Stepanova
Center for Prevention and Control of AIDS and Infectious Diseases; Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Stepanova Elena V., Dr. of Sci. (Med.), Professor, Center for Prevention and Control of AIDS and Infectious Diseases; Professor, Pavlov University
179, Obvodny Canal Embankment, Saint Petersburg, 198103
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Author declares no conflict of interest.
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For citations:
Koloteva A.V., Bazyuk E.M., Shuleshova N.V., Vinogradova T.N., Stepanova E.V. A rare case of toxoplasmosis encephalomyelitis in a patient with HIV infection. The Scientific Notes of the Pavlov University. 2026;33(1):133-141. (In Russ.) https://doi.org/10.24884/1607-4181-2026-33-1-133-141
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