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Hemimasticatory spasm. Own experience of using botulinum neuroprotein type A

https://doi.org/10.24884/1607-4181-2021-28-3-47-51

Abstract

Нemimasticatory spasm (HMS) is a rare disorder of the nervous system, in which there are unilateral, violent spasms of the masticatory muscles innervated by the motor portion of the trigeminal nerve. The causes of HMS remain largely unexplored, but microvascular compression is most likely. Anticonvulsants, surgical treatment and botulinum therapy can be applied for the treatment of HMS.

We presented a clinical case of HMS in a 38-year-old woman who had been suffering from this disease for 18 years. The diagnosis of HMS was established only 10 years after the first visit to the doctor. Spasms could occur up to several hundred times a day with a duration up to 15 seconds. The magnetic resonance imaging allowed to exclude neurovascular conflict. Electroneuromyography revealed axonal lesion of the right trigeminal motor root and spontaneous activity in the right masseter muscle. Anticonvulsant treatment was ineffective. The patient received botulinum therapy with a good treatment result.

About the Authors

A. N. Korenko
Pavlov University
Russian Federation

Korenko Aleksei N., Cand. of Sci. (Med.), Assistant of the Department of Neurology

6-8, L’va Tolstogo str., Saint Petersburg, 197022


Competing Interests:

Authors declare no conflict of interest



A. V. Amelin
Pavlov University
Russian Federation

Amelin Alexander V., Dr. of Sci. (Med.), Professor of the Department of Neurology

6-8, L’va Tolstogo str., Saint Petersburg, 197022


Competing Interests:

Authors declare no conflict of interest



A. A. Timofeeva
Pavlov University
Russian Federation

Timofeeva Alla A., Cand. of Sci. (Med.), Associate Professor of the Department of Neurology

6-8, L’va Tolstogo str., Saint Petersburg, 197022


Competing Interests:

Authors declare no conflict of interest



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Korenko A.N., Amelin A.V., Timofeeva A.A. Hemimasticatory spasm. Own experience of using botulinum neuroprotein type A. The Scientific Notes of the Pavlov University. 2021;28(3):47-51. (In Russ.) https://doi.org/10.24884/1607-4181-2021-28-3-47-51

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