THE CLINICAL CASE OF PRIMARY PROGRESSIVE APHASIA
https://doi.org/10.24884/1607-4181-2019-26-1-61-67
Abstract
The article described the rare clinical case of the patient with probable transmissible encephalopathy (Creutzfeldt–Jakob disease) in whom rapidly forming primary progressive aphasia was the herald clinical feature, and motor and sensory functions were preserved. Creutzfeldt–Jakob disease was diagnosed, and it was confirmed by clinical picture with fast progression of the disease, together with neurovisualization (brain magnetic resonance imaging, FLAIR and DWI options) and electroencephalography pattern. Other possible causes of primary progressive aphasia were excluded.
About the Authors
Natalya V. Shuleshova
Pavlov University
Russian Federation
6-8 L’va Tolstogo street, St. Petersburg, 197022.
Russian Federation
6-8 L’va Tolstogo street, St. Petersburg, 197022.
Aleksey V. Sizov
St. Petersburg State Pediatric Medical University
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
Irina V. Kupriianova
City Multi-field Hospital № 2
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
Victoria V. Zvereva
City Multi-field Hospital № 2
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
References
1. Primary progressive aphasia. Internetcourse. Available at: https://memini.ru/glossary/29336 (accessed 18.04.2019).
2. Primary progressive aphasia. Internetcourse. Available at: https://laesus-de-liro.livejournal.com/391517.html (accessed 18.04.2019).
3. Gorno-Tempini M. L., Hillis A. E., Weintraub S. et al. Classification of primary progressive aphasia and its variants. Neurology. 2011;76(11):1006–1014.
4. Grishina D. A. Speech disturbances in neurodegenerative diseases. Effectivnaya farmakoterapia. 2017;(31). (In Russ.).
5. Stepkina D. A., Zakharov V. V., Yakhno N. N. The syndrome of primary progressive aphasia // Nevrologicheskyi journal. 2014;(5). (In Russ.).
6. Yakhno N. N., Drokonova O. O., Yavorskaya S. A., Voskresenskaya O. N., Damulin I. V. Cortico-basal degeneration syndrome with primary progressive aphasia. Nevrologicheskyi journal. 2014;(4) (In Russ.).
7. Aphasia primary progressive. Internetcourse. Available at: http://www.dnalab.ru/diseases-diagnostics/aphasia-primaryprogressive (accessed 18.04.2019).
8. David Y. Johnson, Diana L. Dunkelberger, Maya Henry, Aissatou Hamanet al. Geschwind Sporadic Jakob-Creutzfeldt disease presenting as primary progressive aphasia. JAMA Neurol. 2013;70(2):254–257.
9. Mandell A. M., Alexander M. P., Carpenter S. Creutzfeldt-Jakob disease presenting as isolated aphasia. Neurology. 1989;39(1):55–58.
10. Shuttleworth E. C., Yates A. J., Paltan-Ortiz J. D. Creutzfeldt-Jakob disease presenting as progressive aphasia. J Natl Med Assoc. 1985;77(8):649–650; 652; 655–656.
11. Geschwind M. D., Cattaruzza T., Vitali P., DeArmond S., Wong K. Brain MRI in sporadic Jakob-Creutzfeldt disease is often misread. Neurology. 2010;74(9 suppl 2):A213.
12. Vitali P., Maccagnano E., Caverzasi E. Diffusionweighted MRI hyperintensity patterns differentiate CJD from other rapid dementias. Neurology. 2011;76(20):1711–1719.
Review
For citations:
Shuleshova N.V., Sizov A.V., Kupriianova I.V., Zvereva V.V. THE CLINICAL CASE OF PRIMARY PROGRESSIVE APHASIA. The Scientific Notes of the Pavlov University. 2019;26(1):61-67. (In Russ.) https://doi.org/10.24884/1607-4181-2019-26-1-61-67
Views:
812
Email this article 