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The first experience of orthotropic implantation of decellularized mitral allograft

https://doi.org/10.24884/1607-4181-2015-22-3-64-65

Abstract

Traditional biological and mechanical valve substitutes have some well-known limitation, such as rapid deterioration of the tissue ones in young patient and the high risk of thrombosis and anticoagulation therapy complications for the mechanical ones. At the same time the aortic and pulmonary valves can already be replaced with decellularized allografts that showed promising results in terms of both hemodynamics and reliability while anticoagulation for them is not needed. This paper describes the first orthotropic implantation of the decellularized mitral valve allograft in sheep model. The original method without stabilizing ring is described, which have shown good echocardiographic results.

About the Authors

P. P. Yablonsky
Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова; Исследовательская лаборатория биотехнологий и искусственных органов имени Г. В. Лейбница Медицинского университета Ганновера
Russian Federation


S. M. Yashin
Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова; Исследовательская лаборатория биотехнологий и искусственных органов имени Г. В. Лейбница Медицинского университета Ганновера
Russian Federation


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Review

For citations:


Yablonsky P.P., Yashin S.M. The first experience of orthotropic implantation of decellularized mitral allograft. The Scientific Notes of the Pavlov University. 2015;22(3):64-65. (In Russ.) https://doi.org/10.24884/1607-4181-2015-22-3-64-65

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ISSN 1607-4181 (Print)
ISSN 2541-8807 (Online)