Features of intestinal ultrasound in patients with complicated course of Crohn’s disease
A. A. Kamanin,
V. P. Morozov,
O. V. Danilchenko,
A. Yu. Korolkov,
V. V. Kostiukov,
A. A. Pomelova,
S. F. Bagnenko https://doi.org/10.24884/1607-4181-2025-32-4-97-102
Abstract
The objective was to study the features of intestinal ultrasound examination in patients with complicated Crohn’s disease (CD). To specify equipment settings and parameters, and to develop ultrasonographic criteria for diagnosing CD complications.
Methods and materials. Intestinal ultrasound was performed in 68 patients with complicated CD. The examinations were conducted using a specific pre-set equipment mode.
Results. New equipment settings for intestinal examination were studied and implemented. Ultrasonographic criteria for inflammatory bowel changes were developed and applied. Ultrasonographic signs of fibrotic changes in the bowel wall were described, along with distinguishing features between inflammatory and fibrotic alterations in the area of intestinal strictures. The application of these new diagnostic techniques in CD patients increased the method’s sensitivity to 90.3–94.1 % and specificity to 97.1–100 % (p<0.05), depending on the disease phenotype.
Conclusions. The implementation of a refined ultrasound examination protocol for patients with Crohn’s disease and the application of established criteria for assessing intestinal inflammatory processes improved the accuracy of diagnosing complications of this disease.
About the Authors
A. A. Kamanin
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Kamanin Alexey A., Cand. of Sci. (Med.), Associate Professor of the Department of General Surgery with the Clinic
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Authors declare no conflict of interest.
V. P. Morozov
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Morozov Victor P., Cand. of Sci. (Med.), Professor, Head of the Department of General Surgery with the Clinic
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Authors declare no conflict of interest.
O. V. Danilchenko
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Danilchenko Olga V., Ultrasound Diagnostics Doctor, SCRC
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Authors declare no conflict of interest.
A. Yu. Korolkov
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Korolkov Andrey Yu., Dr. of Sci. (Med.), Professor, Head of the Department of Hospital Surgery № 2 with the Clinic named after Academician F. G. Uglov, Head of the Department of General and Emergency Surgery, Research Institute of Surgery and Emergency Medicine
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Authors declare no conflict of interest.
V. V. Kostiukov
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Kostiukov Vladislav V., Clinical Resident of the Department of General Surgery with the Clinic
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Authors declare no conflict of interest.
A. A. Pomelova
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Pomelova Anastasia A., Surgeon, Senior Laboratory Assistant at the Department of General Surgery with the Clinic
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Authors declare no conflict of interest.
S. F. Bagnenko
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Bagnenko Sergey F., Dr. of Sci. (Med.), Academician of the Russian Academy of Sciences, Rector
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Authors declare no conflict of interest.
References
1. Sandborn W. J., Feagan B. G., Hanauer S. B. et al. A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn”s disease // Gastroenterology. 2002;122:512–30.
2. Donnellan C. F., Yann L. H., Lal S. Nutritional management of Crohn’s disease // Therap. Adv. Gastroenterol. 2013;6:231– 242. https://doi.org/10.1177/1756283X13477715.
3. Belousova E. A., Shelygin Yu. A., Achkasov S. I. et al. Clinical and Demographic Features and Treatment Approaches for Inflammatory Bowel Diseases (Crohn’s Disease, Ulcerative Colitis) in the Russia // The Primery Results of the Analysis of the National Register. Koloproktologia. 2023;22(1):65–82. https://doi.org/10.33878/2073-7556-2023-22-1-65-82.
4. Shelygin Yu. A., Ivashkin V. T., Achkasov S. I. et al. Clinical guidelines. Crohn’s disease (К50), adults // Koloproktologia. 2023;22(3):10–49. https://doi.org/10.33878/2073-7556-2023-22-3-10-49.
5. Chatu S., Subramanian V., Pollok R. C. Meta-analysis: diagnostic medical radiation exposure in inflammatory bowel disease // Aliment. Pharmacol. Ther. 2012;35:529–539.
6. Zarodnyuk I. V., Eligulashvili R. R., Veselov V. V. et al. Magnetic resonance enterocolonography for assessing inflammation activity in Crohn’s disease using the CDMI and MEGS indices // Koloproktologia. 2022;21(4):39–48. https://doi.org/10.33878/10.33878/2073-7556-2022-21-4-39-48.
7. Bots S., Nylund K., Löwenberg M. et al. Ultrasound for Assessing Disease Activity in IBD Patients: A Systematic Review of Activity Scores // J Crohns Colitis. 2018;12, № 8:920–929. https://doi.org/10.1093/ecco-jcc/jjy048.
8. Nelasov N. J., Karkoshka T. A., Eroshenko O. L. et al. Differential Diagnosis of Inflammatory Bowel Disease and Functional Bowel Disorder in Children Based on Ultrasonography // Innovative Medicine of Kuban. 2024;(2):56–63. (In Russ.). https://doi.org/10.35401/2541-9897-2024-9-2-56-63.
9. Allocca M., Fiorino G., Bonifacio C. et al. Comparative accuracy of bowel ultrasound versus magnetic resonance enterography in combination with colonoscopy in assessing Crohn’s disease and guiding clinical decision-making // J. Crohns Colitis. 2018;12:1280–1287. https://doi.org/10.1093/ecco-jcc/jjy093.
Review
For citations:
Kamanin A.A., Morozov V.P., Danilchenko O.V., Korolkov A.Yu., Kostiukov V.V., Pomelova A.A., Bagnenko S.F. Features of intestinal ultrasound in patients with complicated course of Crohn’s disease. The Scientific Notes of the Pavlov University. 2025;32(4):97-102. (In Russ.) https://doi.org/10.24884/1607-4181-2025-32-4-97-102
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