A clinical case of CADASIL syndrome in a patient after a new coronavirus infection COVID-19
https://doi.org/10.24884/1607-4181-2023-30-1-78-85
Abstract
CADASIL-cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy is the most common form of hereditary cerebral angiopathy and is characterized by recurrent subcortical ischemic strokes, migraine with aura, and cognitive impairment. The article presents clinical case of the female patient with newly diagnosed CADASIL syndrome, who was admitted to the clinic for a course of rehabilitation treatment three months after the onset of an acute cerebrovascular accident caused by a combination of congenital and infectious angiopathy. The combination of CADASIL syndrome and coronavirus infection COVID-19 caused by the SARS-CoV-2 manifested by an acute cerebrovascular accident and the occurrence of focal neurological signs. There was a positive trend in the form of a partial regression of neurological signs against the background of repeated courses of rehabilitation treatment, including physical exercises, mechanotherapy, physiotherapy and acupuncture.
About the Authors
Z. Sh. Dzhalilova
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Dzhalilova Zeyva Sh., Clinical Resident of the Department of Neurology
6-8 L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Authors declare no conflict of interest
E. A. Gavrilova
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Gavrilova Evgeniia A., Neurologist and Acupuncturist of the Neurological Department № 2 of the Clinic of the Research Institute of Neurology
6-8 L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Authors declare no conflict of interest
A. A. Yakovlev
Pavlov University;
North-Western State Medical University named after I. I. Mechnikov
Russian Federation
Competing Interests:
Russian Federation
Yakovlev Aleksei A., Cand. of Sci. (Med), Doctor of the Highest Category, Neurologist, Doctor of Physical Therapy and Sports Medicine, Reflexologist, Head of the Neurological Department № 2 of the Clinic of the Research Institute of Neurology, Assistant of the Department of Neurology and Manual Medicine; Assistant of the Department of Physical Therapy and Sports Medicine
6-8 L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Authors declare no conflict of interest
A. G. Smochilin
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Smochilin Andrei G., Neurologist of the Neurological Department № 2 of the Clinic of the Research Institute of Neurology, Candidate and Assistant of the Department of Neurology and Manual Medicine
6-8 L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
Authors declare no conflict of interest
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For citations:
Dzhalilova Z.Sh., Gavrilova E.A., Yakovlev A.A., Smochilin A.G. A clinical case of CADASIL syndrome in a patient after a new coronavirus infection COVID-19. The Scientific Notes of the Pavlov University. 2023;30(1):78-85. (In Russ.) https://doi.org/10.24884/1607-4181-2023-30-1-78-85
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