NEUROMYELITIS OPTICA SPECTRUM DISORDERS: DIAGNOSIS AND TREATMENT, THE EXPERIENCE OF CLINICAL OBSERVATIONS
https://doi.org/10.24884/1607-4181-2018-25-3-7-13
Abstract
Neuromyelitis optica spectrum disorder (NMOSD) is an aggregate of inflammatory and autoimmune disorders of the central nervous system characterized by recurrent, disabling clinical course and damages predominantly targeting optic nerves, brain stem and spinal cord. NMOSD is stratified into two types: seropositive for aquaporin-4 antibodies (AQP4-IgG) and seronegative, which is reported in 25 % of cases. This article presents modern conceptualizations of NMOSD and describes authors’ own experience of clinical observation of patients.
About the Authors
V. D. Piven
Pavlov University.
Russian Federation
6-8 L’va Tolstogo street, Saint-Petersburg, Russia, 197022.
Russian Federation
6-8 L’va Tolstogo street, Saint-Petersburg, Russia, 197022.
V. S. Krasnov
Pavlov University.
6-8 L’va Tolstogo street, Saint-Petersburg, Russia, 197022.
6-8 L’va Tolstogo street, Saint-Petersburg, Russia, 197022.
A. S. Novikova
Pavlov University.
6-8 L’va Tolstogo street, Saint-Petersburg, Russia, 197022.
6-8 L’va Tolstogo street, Saint-Petersburg, Russia, 197022.
F. M. Piven
Pavlov University.
6-8 L’va Tolstogo street, Saint-Petersburg, Russia, 197022.
6-8 L’va Tolstogo street, Saint-Petersburg, Russia, 197022.
Ya. B. Kushnir
Pavlov University.
6-8 L’va Tolstogo street, Saint-Petersburg, Russia, 197022.
6-8 L’va Tolstogo street, Saint-Petersburg, Russia, 197022.
N. A. Totolian
Pavlov University.
6-8 L’va Tolstogo street, Saint-Petersburg, Russia, 197022.
6-8 L’va Tolstogo street, Saint-Petersburg, Russia, 197022.
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Review
For citations:
Piven V.D., Krasnov V.S., Novikova A.S., Piven F.M., Kushnir Ya.B., Totolian N.A. NEUROMYELITIS OPTICA SPECTRUM DISORDERS: DIAGNOSIS AND TREATMENT, THE EXPERIENCE OF CLINICAL OBSERVATIONS. The Scientific Notes of the Pavlov University. 2018;25(3):7-13. (In Russ.) https://doi.org/10.24884/1607-4181-2018-25-3-7-13
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