Preview

The Scientific Notes of the Pavlov University

Advanced search

Prophylaxis of postoperative hypocalcemia in patients with diffuse toxic goiter

Abstract

In recent years, the surgical treatment of DTG includes extirpation of the thyroid gland that can lead to the development of postoperative hypocalcemia, which causes of development are under study. Up to now, there are no clear recommendations for prophylaxis of postoperative hypocalcemia. In this connection, it is actually to carry out additional research to explore the methods of prophylaxis of postoperative hypocalcemia. The study involved 57 patients with diffuse toxic goiter, who had extirpation of the thyroid gland in period from 2010 until 2015. According to results of the performed study, it has been shown that prophylactic administration of preparations of calcium and vitamin D reduces the risk of postoperative hypocalcemia for patients with vitamin D deficiency.

About the Authors

M. B. Gudieva
Pavlov First Saint Petersburg State Medical University; Federal Almazov North-West Medical Research Centre
Russian Federation


S. V. Dora
Pavlov First Saint Petersburg State Medical University; Federal Almazov North-West Medical Research Centre
Russian Federation


A. R. Volkova
Pavlov First Saint Petersburg State Medical University; Federal Almazov North-West Medical Research Centre
Russian Federation


N. E. Peikrshvili
Pavlov First Saint Petersburg State Medical University; Federal Almazov North-West Medical Research Centre
Russian Federation


E. S. Shilova
Pavlov First Saint Petersburg State Medical University; Federal Almazov North-West Medical Research Centre
Russian Federation


References

1. Болезни щитовидной железы / под ред. Л. И. Бравермана; пер. с англ. — М., 2000. - 432 с.

2. Герасимов Г. А., Мельниченко Г. А., Петунина Н. А., Федак И. Р. Современные представления о лечении тиреотоксикоза радиоактивным йодом // Проблемы эндокринол. — 1997. — Т. 40. — № 1. — С. 28 — 31.

3. Мануйлова Ю. А., Свиридонова М. А., Шведова А. Е. Прогностические факторы послеоперационной гипокальциемии // Клин. и эксперимент. тиреоидол. — 2014. — № 4. — Т. 10. — С. 42.

4. Симакина О. В., Латкина Н. В., Кузнецов Н. С. Факто¬ры, определяющие развитие гипокальциемии у пациентов с болезнью Грейвса после тиреоидэктомии // Клин. и эксперимент. тиреоидол. — № 2. — Т. 10. — С. 43 — 48.

5. Хирургическая эндокринология: руководство / под ред. А. П. Калинина, Н. А. Майстренко, П. С. Ветшева. — СПб., 2004. — 941 с.

6. Annerbo M., Hultin H., StalbergP., Hellman P. Left-shifted relation between calcium and parathyroid hormone in Graves' disease // J. Clin. Endocrinol. Metab. — 2014. — № 99 (2). — Р. 545 — 551. doi: 10.1210/jc. 2013-2500.

7. Cavicchi O., Piccin O, Caliceti U. Transient hypoparathyroidism following thyroidectomy: a prospective study and multivariate analysis of 604 consecutive patients // Otolaryngol. Head Neck. Surg. — 2007. — № 137. — Р. 654 — 658.

8. Chapman D. B., French C. C., LengX. Parathyroid hormone early percent change: an individualized approach to predict postthyroidectomy hypocalcemia // Am. J. Otolaryngol. — 2012. — № 33. — Р. 216 — 220.

9. http://www.endocrincentr.ru/images/material-images/tireo.pdf.

10. http://www.endocrincentr.ru/images/material.

11. Pesce C. E., Shiue Z, Tsai H. Postoperative hypocalcemia after thyroidectomy for Gravesdisease // Thyroid. — 2010. — № 20. — Р. 1279—1283.

12. Yamashita H., Murakami T., Noguchi S. Postoperative tetany in Graves disease. Important role of vitamin D metabolites // Ann. Surg. — 1998. — № 229. — Р. 237 — 245.


Review

For citations:


Gudieva M.B., Dora S.V., Volkova A.R., Peikrshvili N.E., Shilova E.S. Prophylaxis of postoperative hypocalcemia in patients with diffuse toxic goiter. The Scientific Notes of the Pavlov University. 2016;23(2):59-61. (In Russ.)

Views: 883


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1607-4181 (Print)
ISSN 2541-8807 (Online)