Human herpes viruses 6 and 7: history and current state of the problem
https://doi.org/10.24884/1607-4181-2025-32-3-22-30
Abstract
The literature review is devoted to human herpes viruses 6 and 7 (HHV-6, HHV-7). The history of the study of exanthem subitum, the discovery of HHV-7, HHV-6 and its types, epidemiology, pathogenesis, stages of infection, clinical features, laboratory diagnosis and treatment are discussed. Despite some progress in the study of HHV-6 and HHV-7, many aspects of their pathogenesis, their relationship to human pathology, and issues of diagnosis and therapy remain unclear. This is manifested by both under-diagnosis of acute forms of the disease and overdiagnosis of latent infection as acute, which leads to irrational therapy of patients. Further research in this area is needed.
Keywords
HHV-6,
HHV-7,
HHV-6 A/B,
iciHHV-6,
exanthem subitum,
febrile seizures,
congenital infection,
PCR,
ganciclovir
About the Authors
M. A. Nikolskiy
Pavlov University
Russian Federation
Russian Federation
Nikolskiy Mikhail A., Cand. of Sci. (Med), Assistant of the Department of Pediatrics, Pediatrician
6-8, L’va Tolstogo str., Saint Petersburg, 197022
D. A. Lioznov
Pavlov University; Smorodintsev Research Institute of Influenza
Russian Federation
Russian Federation
Lioznov Dmitrii A., Dr. of Sci. (Med), Professor, Head of the Department of Infectious Diseases and Epidemiology; Director
6-8, L’va Tolstogo str., Saint Petersburg, 197022
15/17, Prof. Popova str., Saint Petersburg, 197022
T. V. Antonova
Pavlov University
Russian Federation
Russian Federation
Antonova Tamara V., Dr. of Sci. (Med), Professor, Professor of the Department of Infectious Diseases and Epidemiology
6-8, L’va Tolstogo str., Saint Petersburg, 197022
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Review
For citations:
Nikolskiy M.A., Lioznov D.A., Antonova T.V. Human herpes viruses 6 and 7: history and current state of the problem. The Scientific Notes of the Pavlov University. 2025;32(3):22-30. (In Russ.) https://doi.org/10.24884/1607-4181-2025-32-3-22-30
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