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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">uzspbgmu</journal-id><journal-title-group><journal-title xml:lang="ru">Учёные записки Первого Санкт-Петербургского государственного медицинского университета имени академика И. П. Павлова</journal-title><trans-title-group xml:lang="en"><trans-title>The Scientific Notes of the Pavlov University</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-4181</issn><issn pub-type="epub">2541-8807</issn><publisher><publisher-name>Academician I.P. Pavlov First St. Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1607-4181-2018-25-2-7-18</article-id><article-id custom-type="elpub" pub-id-type="custom">uzspbgmu-482</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>МЕДИКО-ГЕНЕТИЧЕСКОЕ КОНСУЛЬТИРОВАНИЕ ПРИ НАСЛЕДСТВЕННЫХ ФОРМАХ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ И РАКА ЯИЧНИКОВ</article-title><trans-title-group xml:lang="en"><trans-title>MEDICAL AND GENETIC COUNSELING OF HEREDITARY BREAST AND OVARIAN CANCER</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лаптиев</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Laptiev</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>197022, Санкт-Петербург, ул. Льва Толстого, д. 6-8</p></bio><bio xml:lang="en"><p>6-8 L’va Tolstogo str., Saint-Petersburg, 197022</p></bio><email xlink:type="simple">telula87@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корженевская</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Korzhenevskaia</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">korgmar@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколенко</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolenko</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">annasokolenko@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иевлева</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Iyevleva</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">aglayai@inbox.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Имянитов</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Imyanitov</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">evgeny@imyanitov.spb.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Научно-исследовательский институт онкологии имени Н. Н. Петрова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Institution «N. N. Petrov Institute of Oncology» of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2018</year></pub-date><volume>25</volume><issue>2</issue><fpage>7</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лаптиев С.А., Корженевская М.А., Соколенко А.П., Иевлева А.Г., Имянитов Е.Н., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Лаптиев С.А., Корженевская М.А., Соколенко А.П., Иевлева А.Г., Имянитов Е.Н.</copyright-holder><copyright-holder xml:lang="en">Laptiev S.A., Korzhenevskaia M.A., Sokolenko A.P., Iyevleva A.G., Imyanitov E.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sci-notes.ru/jour/article/view/482">https://www.sci-notes.ru/jour/article/view/482</self-uri><abstract><p>Наследственный рак молочной железы и яичников является одной из самых распространенных генетических патологий. Медико-генетическое консультирование пациентов с наследственными формами рака и членов их семей является неотъемлемой составляющей оказания онкологической помощи, так как позволяет разработать комплекс диагностических, профилактических и лечебных мероприятий, направленных на наблюдение за здоровыми индивидуумами и создание персонифицированных подходов к лечению пациентов.</p></abstract><trans-abstract xml:lang="en"><p>Hereditary breast and ovarian cancer is one of the most common genetic pathology. Medical and genetic counseling of patients with hereditary breast and ovarian cancer and their families plays the important role in cancer care, as it helps to develop the set of diagnostic, preventive and therapeutic measures aimed at monitoring healthy individuals and to create personalized approaches to the treatment of patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>семейные формы рака</kwd><kwd>наследственный рак молочной железы и рак яичников</kwd><kwd>гены BRCA 1/2</kwd><kwd>медико-генетическое консультирование</kwd><kwd>профилактика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>familial cancer</kwd><kwd>hereditary breast and ovarian cancer</kwd><kwd>genes BRCA 1/2</kwd><kwd>medical and genetic counseling</kwd><kwd>preventive care</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Каприн А. Д., Старинский В. В., Петрова Г. В. 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