uzspbgmuУчёные записки Первого Санкт-Петербургского государственного медицинского университета имени академика И. П. ПавловаThe Scientific Notes of the Pavlov University1607-41812541-8807Academician I.P. Pavlov First St. Petersburg State Medical University10.24884/1607-4181-2017-24-4-7-12uzspbgmu-469Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESСОВРЕМЕННАЯ СТРАТЕГИЯ ЛЕЧЕНИЯ БОЛЬНЫХ С КАРЦИНОМАТОЗОМ БРЮШИНЫMODERN STRATEGY IN TREATMENT OF PERITONEAL CARCINOMATOSISЗахаренкоА. А.ZakharenkoA. A.

Александр Анатольевич Захаренко - доктор медицинских наук, заместитель главного врача по онкологии, руководитель отдела онкохирургии НИИ хирургии и неотложной медицины, профессор кафедры онкологии

Alexander Anatolievich Zakharenko

9516183@mail.ruЗайцевД. А.ZaitcevD. A.

Данила Александрович Зайцев - очный аспирант НИИ хиругии и неотложной медицины, хирург, онколог.

Ул. Льва Толстого, д. 6-8, Санкт-Петербург, 197022

nu_nrg@mail.ruБеляевМ. А.BelyaevM. A.

Михаил Алексеевич Беляев - кандидат медицинских наук, руководитель отделения абдоминальной хирургии НИИ хирургии и неотложной хирургии ПСПбГМУ им.акад. И.П.Павлова, хирург, онколог

Mihkail Alexeevich Belyaev

8628926@mail.ruТрушинА. А.TrushinA. A.

Антон Александрович Трушин - заведующий отделения абдоминальной онкологии НИИ хирургии и неотложной хирургии ПСПбГМУ им.акад. И.П.Павлова, хирург, онколог

Anton Alexandrovich Trushin

anton.trushin@mail.ruТенО. А.TenO. A.

Олег Андреевич Тен - врач онколог отделения абдоминальной онкологии НИИ хирургии и неотложной хирургии ПСПбГМУ им.акад. И.П.Павлова, хирург

Oleg Andreevich Ten

ten888oleg@mail.ruВовинК. Н.NatkhaA. S.nauka@spb-gmu.ruНатхаА. С.VovinK. N.nauka@spb-gmu.ruРыбальченкоВ. А.RybalchenkoV. A.

Vitaliy Alexandrovich Rybalchenko

vr9650765236@yandex.ruФедеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Educational Institution of Higher Education «Academician I. P. Pavlov First Saint-Petersburg State Medical University» of the Ministry of Healthcare of the Russian FederationRussian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Educational Institution of Higher Education «Academician I. P. Pavlov First Saint-Petersburg State Medical University» of the Ministry of Healthcare of the Russian FederationRussian Federation201730122017244712Copyright © Захаренко А.А., Зайцев Д.А., Беляев М.А., Трушин А.А., Тен О.А., Вовин К.Н., Натха А.С., Рыбальченко В.А., 20172017Захаренко А.А., Зайцев Д.А., Беляев М.А., Трушин А.А., Тен О.А., Вовин К.Н., Натха А.С., Рыбальченко В.А.Zakharenko A.A., Zaitcev D.A., Belyaev M.A., Trushin A.A., Ten O.A., Natkha A.S., Vovin K.N., Rybalchenko V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sci-notes.ru/jour/article/view/469

Карциноматоз брюшины (КБ) – частое проявление прогрессирования злокачественных заболеваний органов брюшной полости и малого таза. В основе современной стратегии лечения КБ лежит концепция регионарного воздействия в виде циторедуктивных операций и внутрибрюшной химиотерапии, доказавшая свою эффективность при лечении распространенных новообразований аппендикса, мезотелиомы брюшины, распространенного колоректального рака, рака яичников и желудка. Однако при существующих четких критериях выполнения циторедуктивных операций мы наблюдаем отсутствие стандартизованного подхода для внутрибрюшной химиотерапии, которая используется в различных вариантах и режимах в современной практике.

Peritoneal carcinomatosis (PC) is a common manifestation of progression in peritoneal and gynecologic malignancies. Current primary strategy in treatment of PC is the concept of regional influence by the way of cytoreductive surgery and intraperitoneal chemotherapy, which has proven the efficiency in treatment of common appendicitis tumors, peritoneum mesothelioma, advanced colorectal cancer, ovarian and gastric cancers. However, in spite of the existing unified criteria for performing cytoreductive surgeries, we observe a lack of a standardized approach for intra-peritoneal chemotherapy, which is used in various variants and regimens in modern clinical practice. Further studies of effectiveness of various intra-peritoneal chemotherapy methods and their combinations are necessary for the development of modern algorithms in treatment of PC.

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The authors declare that there are no conflicts of interest present.