uzspbgmuУчёные записки Первого Санкт-Петербургского государственного медицинского университета имени академика И. П. ПавловаThe Scientific Notes of the Pavlov University1607-41812541-8807Academician I.P. Pavlov First St. Petersburg State Medical University10.24884/1607-4181-2017-24-4-13-20uzspbgmu-441Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESВОЗМОЖНОСТИ МАММОПЛАСТИКИ С ИСПОЛЬЗОВАНИЕМ ТРАНСПЛАНТАЦИИ АУТОЛОГИЧНОЙ ЖИРОВОЙ ТКАНИ, ОБОГАЩЕННОЙ СТВОЛОВЫМИ КЛЕТКАМИTHE POSSIBILITIES OF MAMMOPLASTY USING THE TRANSPLANTATION OF AUTOLOGOUS ADIPOSE TISSUE ENRICHED WITH STEM CELLSРоманенковН. С.RomanenkovN. S.

Николай Сергеевич Романенков.

Ул. Шкапина, д. 30, Санкт-Петербург, 198095

Nikolay S. Romanenkov.

Shkapina street, 30, Saint-Petersburg, 198095

nickrom@inbox.ruМовчанК. Н.MovchanK. N.

Константин Николаевич Мовчан

movchank@spbmiac.ruСанкт-Петербургское государственное бюджетное учреждение здравоохранения «Медицинский информационно-аналитический центр»РоссияSt. Petersburg State Budget funded Healthcare Institution Medical Information and Analytical CenterRussian Federation2017301220172441320Copyright © Романенков Н.С., Мовчан К.Н., 20172017Романенков Н.С., Мовчан К.Н.Romanenkov N.S., Movchan K.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sci-notes.ru/jour/article/view/441

Сведения, приводимые в источниках научной литературы о трансплантации аутологичной жировой ткани (АЖТ), обогащенной стволовыми клетками (СК), при коррекции формы и объема молочных желез (как по эстетическим показаниям, так и в случаях устранения послеоперационных деформаций), характеризуются неоднозначностью результатов. Это обстоятельство оказывается побудительным мотивом для целенаправленного изучения возможностей современных хирургических технологий в применении мезенхимальных СК (МСК) из аутологичной жировой ткани при маммопластике. Проанализированы сведения о методических основах изоляции МСК из собственной жировой ткани пациентов. Отдельно изучены данные о цитологических критериях, на основании которых полученный биологический субстрат может быть отнесен к категории СК. Продемонстрированы технические особенности трансплантации СК, полученных из АЖТ, в случаях выполнения маммопластики. По мнению компетентных исследователей, устранение деформаций молочных желез с применением клеточных технологий – перспективное научное направление медицины.

The information given in the scientific literature sources about the transplantation of autologous adipose tissue (AAT) enriched with stem cells (SC) in cases of breast shape and volume correction (in both aesthetic indications and elimination of postoperative deformities) is characterized by versatile results. This circumstance promotes the purposeful study about the possibilities of modern surgical technologies in use of mesenchymal SC (MSCs) of autologous adipose tissue in cases of mammoplasty. The information on the basic techniques of mesenchymal SC isolation from the AAT has been analyzed. The data of cytological criteria were studied separately that allow to relate this biological substance to the SC. Technical features of stem cells transplantation derived from the autologous adipose transplant in cases of mammoplasty are demonstrated. According to opinion among the competent researchers, elimination of postoperative deformities using cellular technologies is a promising scientific direction of medicine.

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The authors declare that there are no conflicts of interest present.