uzspbgmuУчёные записки Первого Санкт-Петербургского государственного медицинского университета имени академика И. П. ПавловаThe Scientific Notes of the Pavlov University1607-41812541-8807Academician I.P. Pavlov First St. Petersburg State Medical University10.24884/1607-4181-2016-23-2-6-11uzspbgmu-322Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESНОВЫЕ ПЕРСПЕКТИВЫ ИСПОЛЬЗОВАНИЯ ГАММА-ГЛУТАМИЛ-ТРАНСПЕПТИДАЗЫ В ЭНЗИМОДИАГНОСТИКЕNew perspectives for use of gamma-glutamyltranspeptidase in clinical enzymes testsАлександроваЛ. А.AlexandrovaL. A.Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. ПавловаРоссияPavlov First Saint Petersburg State Medical UniversityRussian Federation201630062016232611Copyright © Александрова Л.А., 20162016Александрова Л.А.Alexandrova L.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sci-notes.ru/jour/article/view/322

Гамма-глутамил-транспептидаза (ГГТП), выделенная из разных источников, от микроорганизмов до млекопитающих, включая кровь и органы человека, достаточно подробно изучена, что позволило по-новому взглянуть на роль этого фермента в клеточном метаболизме, патогенезе ряда заболеваний и применении его в клинической медицине. Накапливаются доказательства в пользу использования ГГТП как надежного маркера прогноза сердечно-сосудистых заболеваний, осложнений диабета 2-го типа, метаболического синдрома. 

Gamma-glutamyltranspeptidase (GGTP), isolated from a variety of sources from microorganisms to mammals, including human blood and organs, has been studied sufficiently detailed, which allowed to take a fresh look at the role of this enzyme in cellular metabolism, the pathogenesis of several diseases and its application in clinical medicine. Evidences in favor of use of GGTP as reliable marker to forecast cardiovascular diseases, and complications of type 2 diabetes of a metabolic syndrome are accumulated. 

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The authors declare that there are no conflicts of interest present.