uzspbgmuУчёные записки Первого Санкт-Петербургского государственного медицинского университета имени академика И. П. ПавловаThe Scientific Notes of the Pavlov University1607-41812541-8807Academician I.P. Pavlov First St. Petersburg State Medical University10.24884/1607-4181-2015-22-4-16-19uzspbgmu-144Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESНЕТЕПЛОВЫЕ ЭФФЕКТЫ ИЗЛУЧЕНИЯ МОБИЛЬНОГО ТЕЛЕФОНА НА ГОЛОВНОЙ МОЗГNon-thermal effects of mobile phone radiation on brainБабалянА. В.BabalyanA. V.noemail@neicon.ruКарелинА. О.KarelinA. O.noemail@neicon.ruПервый Санкт-Петербургский государственный медицинский университет имени академика И.П. ПавловаRussian Federation2015301220152241619Copyright © Бабалян А.В., Карелин А.О., 20152015Бабалян А.В., Карелин А.О.Babalyan A.V., Karelin A.O.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sci-notes.ru/jour/article/view/144

Данная статья представляет обзор экспериментальных исследований, посвященных влиянию излучения мобильного телефона на головной мозг. Для статьи были отобраны наиболее значимые и фундаментальные исследования зарубежных авторов. Проведен анализ имеющихся противоречивых данных о воздействии излучения мобильного телефона на когнитивные функции, электрофизиологию головного мозга, проницаемость гемато-энцефалического барьера и возникновение субъективных жалоб.

This article gives a review of major experimental studies devoted to the effect of mobile phone electromagnetic emission on brain. The most relevant and fundamental studies were reviewed. Both positive and negative results were analyzed to give a straight answer, if mobile phone emission effects brain electrophysiology, cognitive function, subjective symptoms and blood-brain barrier permeability.

когнитивные функцииэлектрофизиологияголовной мозгжалобыгематоэнцефалический барьермобильный телефонизлучениеcognitive functionblood-brain barriersymptomsbrainelectrophysiologymobile phoneemissionReferencesСанПиН 2.1.8/2.2.4.1190-03 «Гигиенические требования к размещению и эксплуатации средств сухопутной подвижной радиосвязи».СанПиН 2.1.8/2.2.4.1190-03 «Гигиенические требования к размещению и эксплуатации средств сухопутной подвижной радиосвязи».Abdel-Rassoul G., El-Fateh O.Л., Salem M.Л. et al. Neurobehavioral effects among inhabitants around mobile phone base stations // Neurotoxicology. - 2007. - № 28. - Р. 434 - 440.Abdel-Rassoul G., El-Fateh O.Л., Salem M.Л. et al. Neurobehavioral effects among inhabitants around mobile phone base stations // Neurotoxicology. - 2007. - № 28. - Р. 434 - 440.Aldad T.S., Gan G., Gao X. B. et al. Fetal radiofrequency radiation exposure from 800-1900 MHz-rated cellular telephones affects neurodevelopment and behavior in mice // Sci Rep. - 2012. - № 2. - Р. 312.Aldad T.S., Gan G., Gao X. B. et al. Fetal radiofrequency radiation exposure from 800-1900 MHz-rated cellular telephones affects neurodevelopment and behavior in mice // Sci Rep. - 2012. - № 2. - Р. 312.Ammari M., Jacquet Л., Lecomte Л. et al. Effect of head-only sub-chronic and chronic exposure to 900-MHz GSM electromagnetic fields on spatial memory in rats // Brain. Inj. - 2008. - № 22 (13-14). - Р. 1021 - 1029.Ammari M., Jacquet Л., Lecomte Л. et al. Effect of head-only sub-chronic and chronic exposure to 900-MHz GSM electromagnetic fields on spatial memory in rats // Brain. Inj. - 2008. - № 22 (13-14). - Р. 1021 - 1029.Arendash G.W., Mori T., Dorsey M. et al. Electromagnetic treatment to old Alzheimer's mice reverses в-amyloid deposition, modifies cerebral blood flow, and provides selected cognitive benefit // PLoS. One. - 2012. - № 7 (4). - Р. e35751.Arendash G.W., Mori T., Dorsey M. et al. Electromagnetic treatment to old Alzheimer's mice reverses в-amyloid deposition, modifies cerebral blood flow, and provides selected cognitive benefit // PLoS. One. - 2012. - № 7 (4). - Р. e35751.Bak M., Dudarewicz A., Zmysмlony M. et al. Effects of GSM signals during exposure to event related potentials (ERPs) // Int. J. Occup. Med. Environ. Health. - 2012. - № 23 (2). - Р. 191 - 199.Bak M., Dudarewicz A., Zmysмlony M. et al. Effects of GSM signals during exposure to event related potentials (ERPs) // Int. J. Occup. Med. Environ. Health. - 2012. - № 23 (2). - Р. 191 - 199.Croft R. J., Leung S., McKenzie R.J. et al. Effects of 2G and 3G mobile phones on human alpha rhythms: Resting EEG in adolescents, young adults, and the elderly // Bioelectromagnetics. - 2012. - № 31 (6). - Р. 434 - 444.Croft R. J., Leung S., McKenzie R.J. et al. Effects of 2G and 3G mobile phones on human alpha rhythms: Resting EEG in adolescents, young adults, and the elderly // Bioelectromagnetics. - 2012. - № 31 (6). - Р. 434 - 444.Fragopoulou A.F., Miltiadous P., Stamatakis A. et al. Whole body exposure with GSM 900MHz affects spatial memory in mice // Pathophysiology. - 2012. - № 17 (3). - Р. 179- 187.Fragopoulou A.F., Miltiadous P., Stamatakis A. et al. Whole body exposure with GSM 900MHz affects spatial memory in mice // Pathophysiology. - 2012. - № 17 (3). - Р. 179- 187.Frey A.H., Feld S.R. Avoidance by rats of illumination with low power nonionizing electromagnetic energy // J. Comp. Physiol. Psychol. - 1975. - № 89. - Р. 183- 188.Frey A.H., Feld S.R. Avoidance by rats of illumination with low power nonionizing electromagnetic energy // J. Comp. Physiol. Psychol. - 1975. - № 89. - Р. 183- 188.Hao D., Yang L., Chen S. et al. Effects of long-term electromagnetic field exposure on spatial learning and memory in rats // Neurol Sci. - 2012.Hao D., Yang L., Chen S. et al. Effects of long-term electromagnetic field exposure on spatial learning and memory in rats // Neurol Sci. - 2012.Inomata-Terada S., Okabe S., Arai N. et al. Effects of high frequency electromagnetic field (EMF) emitted by mobile phones on the human motor cortex // Bioelectromagnetics. - 2007. - № 28 (7). - Р. 553 - 561.Inomata-Terada S., Okabe S., Arai N. et al. Effects of high frequency electromagnetic field (EMF) emitted by mobile phones on the human motor cortex // Bioelectromagnetics. - 2007. - № 28 (7). - Р. 553 - 561.Finnie J.W., Blumbergs P.C., Manavis J. et al. Effect of long-term mobile communication microwave exposure on vascular permeability in mouse brain // Pathology. - 2002. - № 34. - Р. 344 - 347.Finnie J.W., Blumbergs P.C., Manavis J. et al. Effect of long-term mobile communication microwave exposure on vascular permeability in mouse brain // Pathology. - 2002. - № 34. - Р. 344 - 347.Kumlin T., Iivonen H., Miettinen P. et al. Mobile phone radiation and the developing brain: behavioral and morphological effects in juvenile rats // Radiat. Res. - 2007. - № 168 (4). - Р. 471-479.Kumlin T., Iivonen H., Miettinen P. et al. Mobile phone radiation and the developing brain: behavioral and morphological effects in juvenile rats // Radiat. Res. - 2007. - № 168 (4). - Р. 471-479.Kundi M., Hutter H. P. Mobile phone base stations - Effects on wellbeing and health // Pathophysiology. - 2009. - № 16. - Р. 123 - 135.Kundi M., Hutter H. P. Mobile phone base stations - Effects on wellbeing and health // Pathophysiology. - 2009. - № 16. - Р. 123 - 135.Leung S., Croft R.J., McKenzie R.J. et al. Effects of 2G and 3G mobile phones on performance and electrophysiology in adolescents, young adults and older adults // Clin. Neurophysiol. - 2011. - № 122 (11). - Р. 2203 - 2216.Leung S., Croft R.J., McKenzie R.J. et al. Effects of 2G and 3G mobile phones on performance and electrophysiology in adolescents, young adults and older adults // Clin. Neurophysiol. - 2011. - № 122 (11). - Р. 2203 - 2216.Loughran S.P., McKenzie R.J., Jackson M.L. et al. Individual differences in the effects of mobile phone exposure on human sleep: rethinking the problem // Bioelectromagnetics. - 2012. - № 33 (1). - Р. 86 - 93.Loughran S.P., McKenzie R.J., Jackson M.L. et al. Individual differences in the effects of mobile phone exposure on human sleep: rethinking the problem // Bioelectromagnetics. - 2012. - № 33 (1). - Р. 86 - 93.Lowden A., Akerstedt T., Ingre M. et al. Sleep after mobile phone exposure in subjects with mobile phone-related symptoms // Bioelectromagnetics. - 2011. - № 32 (1). - Р. 4-14.Lowden A., Akerstedt T., Ingre M. et al. Sleep after mobile phone exposure in subjects with mobile phone-related symptoms // Bioelectromagnetics. - 2011. - № 32 (1). - Р. 4-14.Kuribayashi M., Wang J., Fujiwara O. et al. Lack of effects of 1439 MHz electromagnetic near field exposure on the blood-brain barrier in immature and young rats // Bioelectromagnetics. - 2005. - № 26. - Р. 578 - 588.Kuribayashi M., Wang J., Fujiwara O. et al. Lack of effects of 1439 MHz electromagnetic near field exposure on the blood-brain barrier in immature and young rats // Bioelectromagnetics. - 2005. - № 26. - Р. 578 - 588.Maganioti A.E., Hountala C.D., Papageorgiou C.C. et al. Principal component analysis of the P600 waveform: RF and gender effects // Neurosci Lett. - 2012. - № 478 (1). - Р. 19 - 23.Maganioti A.E., Hountala C.D., Papageorgiou C.C. et al. Principal component analysis of the P600 waveform: RF and gender effects // Neurosci Lett. - 2012. - № 478 (1). - Р. 19 - 23.Merritt J.H., Chamness A.F., Allens S.J. Studies on blood-brain barrier permeability after microwave radiation // Radiat. Environ. Biophys. - 1978. - № 15. - Р. 367 - 377.Merritt J.H., Chamness A.F., Allens S.J. Studies on blood-brain barrier permeability after microwave radiation // Radiat. Environ. Biophys. - 1978. - № 15. - Р. 367 - 377.Mohler E., Frei P., Fro?hlich J. et al. QUALIFEX-team. Exposure to radiofrequency electromagnetic fields and sleep quality: a prospective cohort study // PLoS One. - 2012. - № 7 (5). - Р. e37455.Mohler E., Frei P., Fro?hlich J. et al. QUALIFEX-team. Exposure to radiofrequency electromagnetic fields and sleep quality: a prospective cohort study // PLoS One. - 2012. - № 7 (5). - Р. e37455.Narayanan S.N., Kumar R.S., Paval J. et al. Analysis of emotionality and locomotion in radio-frequency electromagnetic radiation exposed rats // Neurol. Sci. - 2012. - № 46.Narayanan S.N., Kumar R.S., Paval J. et al. Analysis of emotionality and locomotion in radio-frequency electromagnetic radiation exposed rats // Neurol. Sci. - 2012. - № 46.Ntzouni M.P., Stamatakis A., Stylianopoulou F. et al. Shortterm memory in mice is affected by mobile phone radiation // Pathophysiology. - 2011. - № 18 (3). - Р. 193- 199.Ntzouni M.P., Stamatakis A., Stylianopoulou F. et al. Shortterm memory in mice is affected by mobile phone radiation // Pathophysiology. - 2011. - № 18 (3). - Р. 193- 199.Oscar K.J., Hawkins, T.D. Microwave alteration of the blood-brain barrier system of rats // Brain. Res. - 1977. - № 126. - Р. 281 - 293.Oscar K.J., Hawkins, T.D. Microwave alteration of the blood-brain barrier system of rats // Brain. Res. - 1977. - № 126. - Р. 281 - 293.Riddervold I.S., Pedersen G.F., Andersen N.T. et al. Cognitive function and symptoms in adults and adolescents in relation to RF radiation from UMTS base stations // Bioelectromagnetics. - 2008. - № 29 (4). - Р. 257 - 267.Riddervold I.S., Pedersen G.F., Andersen N.T. et al. Cognitive function and symptoms in adults and adolescents in relation to RF radiation from UMTS base stations // Bioelectromagnetics. - 2008. - № 29 (4). - Р. 257 - 267.Sauter C., Dorn H., Bahr A. et al. Effects of exposure to electromagnetic fields emitted by GSM 900 and WCDMA mobile phones on cognitive function in young male subjects // Bioelectromagnetics. - 2011. - № 32 (3). - Р. 179-190.Sauter C., Dorn H., Bahr A. et al. Effects of exposure to electromagnetic fields emitted by GSM 900 and WCDMA mobile phones on cognitive function in young male subjects // Bioelectromagnetics. - 2011. - № 32 (3). - Р. 179-190.Schmid M.R., Murbach M., Lustenberger C. Sleep EEG alterations: effects of pulsed magnetic fields versus pulse-modulated radio frequency electromagnetic fields // J. Sleep. Res. - 2012.Schmid M.R., Murbach M., Lustenberger C. Sleep EEG alterations: effects of pulsed magnetic fields versus pulse-modulated radio frequency electromagnetic fields // J. Sleep. Res. - 2012.Sokolovic D., Djordjevic B., Kocic G. et al. The effect of melatonin on body mass and behaviour of rats during an exposure to microwave radiation from mobile phone // Bratisl. Lek. Listy. - 2012. - № 113 (5). - Р. 265 - 269.Sokolovic D., Djordjevic B., Kocic G. et al. The effect of melatonin on body mass and behaviour of rats during an exposure to microwave radiation from mobile phone // Bratisl. Lek. Listy. - 2012. - № 113 (5). - Р. 265 - 269.Stovner L.J., Oftedal G., Straume A. et al. Nocebo as headache trigger: evidence from a sham-controlled provocation study with RF fields // Acta Neurol. Scand. Suppl. - 2008. - № 188. - Р. 67 - 71.Stovner L.J., Oftedal G., Straume A. et al. Nocebo as headache trigger: evidence from a sham-controlled provocation study with RF fields // Acta Neurol. Scand. Suppl. - 2008. - № 188. - Р. 67 - 71.Tombini M., Pellegrino G., Pasqualetti P. et al. Mobile phone emissions modulate brain excitability in patients with focal epilepsy // Brain. Stimul. - 2012.Tombini M., Pellegrino G., Pasqualetti P. et al. Mobile phone emissions modulate brain excitability in patients with focal epilepsy // Brain. Stimul. - 2012.Trunk A., Stefanics G., Zentai N. et al. No effects of a single 3G UMTS mobile phone exposure on spontaneous EEG activity, ERP correlates, and automatic deviance detection // Bioelectromagnetics. - 2012.Trunk A., Stefanics G., Zentai N. et al. No effects of a single 3G UMTS mobile phone exposure on spontaneous EEG activity, ERP correlates, and automatic deviance detection // Bioelectromagnetics. - 2012.Vecchio F., Buffo P., Sergio S. et al. Mobile phone emission modulates event-related desynchronization of a rhythms and cognitive-motor performance in healthy humans // Clin. Neurophysiol. - 2012. - № 123 (1). - Р. 121 - 128.Vecchio F., Buffo P., Sergio S. et al. Mobile phone emission modulates event-related desynchronization of a rhythms and cognitive-motor performance in healthy humans // Clin. Neurophysiol. - 2012. - № 123 (1). - Р. 121 - 128.Vecchio F., Tombini M., Buffo P. et al. Mobile phone emission increases inter-hemispheric functional coupling of electroencephalographic alpha rhythms in epileptic patients // Int. J. Psychophysiol. - 2012. - № 84 (2). - Р. 164-171.Vecchio F., Tombini M., Buffo P. et al. Mobile phone emission increases inter-hemispheric functional coupling of electroencephalographic alpha rhythms in epileptic patients // Int. J. Psychophysiol. - 2012. - № 84 (2). - Р. 164-171.Ward T.R., Elder J.A., Long M.D. et al. Measurement of blood-brain barrier permeation in rats during exposure to 2450-MHz microwaves // Bioelectromagnetics. - 1982. - № 3. - Р. 371-383.Ward T.R., Elder J.A., Long M.D. et al. Measurement of blood-brain barrier permeation in rats during exposure to 2450-MHz microwaves // Bioelectromagnetics. - 1982. - № 3. - Р. 371-383.Wiholm C., Lowden A., Kuster N. et al. Mobile phone exposure and spatial memory // Bioelectromagnetics. - 2009. - № 30 (1). - Р. 59 - 65.Wiholm C., Lowden A., Kuster N. et al. Mobile phone exposure and spatial memory // Bioelectromagnetics. - 2009. - № 30 (1). - Р. 59 - 65.

The authors declare that there are no conflicts of interest present.